The Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy (SADI-S) is an advanced bariatric surgery designed to promote significant weight loss and metabolic improvements. This procedure combines two key components: a sleeve gastrectomy, which reduces stomach size, and a duodeno-ileal bypass, which alters the digestive process to limit calorie absorption. The SADI-S shares similarities with the standard duodenal switch but is a more streamlined procedure, requiring less time to complete since it involves only one surgical bowel connection.
SADI-S
SADI-S
The SADI-S procedure begins similarly to a sleeve gastrectomy, where a large portion of the stomach is removed, leaving behind a smaller, tube-shaped stomach. Next, the upper section of the small intestine is separated just beyond the stomach. A segment of the lower small intestine is then measured and connected directly to the stomach, creating a single connection point, which simplifies the procedure compared to other bypass surgeries.
After surgery, food moves from the newly shaped stomach directly into the lower part of the small intestine, bypassing a portion of the digestive tract. Once there, it combines with digestive enzymes from the bypassed section, ensuring adequate absorption of essential vitamins and minerals. This procedure not only supports significant weight loss but also helps reduce hunger, increase feelings of fullness, regulate blood sugar, and improve or even resolve type 2 diabetes.
SADI-S is an effective procedure for long-term weight loss and type 2 diabetes remission. It is simpler and faster than gastric bypass or BPD-DS, making it a good option for those needing additional weight loss after a sleeve gastrectomy. However, it requires lifelong vitamin supplementation due to reduced nutrient absorption. As a newer procedure, long-term data is limited, yet some patients may experience acid reflux or more frequent bowel movements.


Before considering the SADI-S, it is important to become familiar with the potential risks of bariatric procedures. Risks vary based on the health of the patient.
- Minor Complications
- Major Complications
- Minor wound or skin infection
- Excess / loose skin
- Vomiting or nausea
- Acid reflux (heartburn)
- Changes in bowel habits like constipation, diarrhea, bloating, cramping, or gas
- Development of gallstones or gallbladder disease
- Nutritional deficiencies as a result of food bypassing the stomach


- Internal bleeding
- Intestinal obstruction
- Blood clots in the legs or lungs
- Internal hernia
- Perforation of stomach/intestine or leakage

